I know this is an old post, but I wanted to add what I’ve learned. I had this Exact same issue (I think) but was able to solve it without a windows reinstall. My system setup is very similar to @Randyre (I have an i5, GTX 1070, and SSD). All I had to do was run my emulator (VPX) in Windowed Mode, NOT in Forced Exclusive Fullscreen Mode. It was that simple.
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